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Abberior Instruments GmbH (Göttingen)

IMAGING BEYOND BARRIERS!

Our new office

We are happy to announce our new office & development center in Basel, Switzerland!

Abberior Instruments GmbH (Göttingen), Zweigniederlassung Basel, Mattenstr. 26, 4058 Basel, Switzerland

email: info@abberior-instruments.ch
 

Correlative microscopy approach for biology using X-ray holography and STED microscopy

Please check out the new Publication (link below): 

(1st row: T. Salditt, M. Bernhardt, S. Köster; 2nd row: M. Osterhoff, H. Mittelstädt, A. Wittmeier)

M. Bernhardt, J.-D. Nicolas, M. Osterhoff, H. Mittelstädt, M. Reuss, B. Harke, A. Wittmeier, M. Sprung, S. Köster, T. Salditt, "Correlative microscopy approach for biology using X-ray holography, X-ray scanning diffraction and STED microscopy", Nature Communications Volume 9, Article number: 3641 (2018)

easy3D STED + RESCue STED = unrivaled 3D STED resolution

Actin stain using Abberior STAR RED Phalloidin. Samples were prepared by Dr. Christian Vogl, InnerEarLab, UMG Göttingen, Germany.

This xz-slice through mouse inner-ear hair cells using easy3D STED and RESCue STED demonstrates the unrivaled performance that can be achived by applying both techniques simultaneously. Since standard 3D superresolution places more photoinduced stress on the marker, the key ingredients that made this image possible where 1st: producing a STED-zero point of exceptional quality using easy3D STED, and 2nd: further reducing the light dose in the sample with RESCue STED.

Three dimensional live-cell STED microscopy at increased depth using a water immersion objective

Our patent protected easy3D STED technology produces superior 3D STED data – please check out our new publication:

Spherical abberations corrected z-STED raw data

J. Heine, C. A. Wurm, J. Keller-Findeisen, A. Schönle, B. Harke, M. Reuss, F. R. Winter, G. Donnert, "Three dimensional live-cell STED microscopy at increased depth using a water immersion objective", Review of Scientific Instruments (2018)

DynamicPLUS

DyMIN STED

easy3D DyMIN STED volume imaging of Neurons with unprecedented resolution!

Confocal vs. DyMIN STED imaging:

Confocal and easy3D DyMIN STED imaging of dendrites in brain slices. GFP-tagged proteins were expressed and immunolabelled using primary antibodies against GFP and secondary antibodies coupled to Abberior STAR 635P. Sample was prepared by O. Kaplan and H. Kawabe @ MPI of Experimental Medicine, Göttingen, Germany. Scale Bar, 2 µm.

DyMIN STED complements our existing list of intelligent STED illumination schemes, namely RESCue STED and MINFIELD STED. All three intelligent illumination schemes for STED dramatically reduce the light irradiation on your sample (DyMIN STED up to two orders of magnitude) and are exclusively available @ Abberior Instruments.

Explanation videos of DyMIN, RESCue and MINFIELD STED:

 

DyMIN STED is a co-development between Stefan Hell and coworkers and Abberior Instruments. Read all technical details in the current PNAS publication, 2017: 

J. Heine, M. Reuss, B. Harke, E. D'Este, S. J. Sahl and S. W. Hell, "Adaptive-illumination STED nanoscopy", PNAS (2017)

Nature review on DyMIN STED: G. Pacchioni, "Always look on the bright side of the fluorophore", Nature Review Materials (2017)

Easy3D STED volume imaging deep in tissue

Surface Rendering of 2 color easy3D STED volumen imaging of a cleared adult kidney sample of a rat.

The Abberior Instruments Team

Get to know a part of our Abberior Instruments Team!

From zero to STED in no time

Follow along with the incredibly quick installation of a STEDYCON super resolution microscope, uncut. We go from opening the carton to the first super-resolution STED image in under three minutes. Don't forget to check out the real time movie here: https://youtu.be/wnFnyt8yJyA

Abberior Instruments easyCommander

Top-notch STED measurements at the highest possible resolution only require a few clicks.

 


easyCommander is Imspector's brand new graphical user interface for Abberior Instruments Expert Line microscopes. 
It largely simplifies your experimental workflow and allows you to acquire STED images with a few clicks.

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